Factor V Leiden mutation frequency and geographical distribution in Turkish population
نویسندگان
چکیده
منابع مشابه
Frequency of factor V Leiden (G1691A) and prothrombin (G20210A) polymorphisms in Population of Kerman Province, Iran
Background & Aims:Thromboembolism is an acute cardiovascular disease that ranges from clinically unimportant to massive embolism. Both acquired and hereditary risk factors contribute to the disease. We aimed to determine the prevalence of two hereditary predisposing factor of the disease, prothrombin G20210A and factor V Leiden (G1691A) polymorphisms, in Kerman population.<br /...
متن کاملFactor V Leiden, MTHFR C677T and Prothrombin Gene Mutation G20210A in Iranian Patients with Venous Thrombosis
Background: Factor V Leiden, Prothrombin gene (G20210A) and MTHFR (C677T) polymorphism are the main biomarkers for evaluation of tendency for venous thromboembolism. We aimed to investigate the frequency of mutations in factor V Leiden, Prothrombin G20210A and MTHFR C677T and identify the genetic status for these mutations in patients with venous thrombosis. Methods: This study was carried out...
متن کاملFrequency of Factor V Leiden and Prothrombin Polymorphism in South of Iran
Normal hemostasis requires balanced regulation of prothrombotic and antithrombotic factors. Inherited alteration of factor V and prothrombin gene, the G20210A mutation, increases the resistance of factor V to degradation and booster production of prothrombin respectively. These alterations can increase hypercoagulability leading to thrombotic consequences. We aimed to assess the frequencies of ...
متن کاملevaluation the frequency of factor v leiden mutation in pregnant women with preeclampsia syndrome in an iranian population
background: role of genetic factors in etiology of preeclampsia is not confirmed yet. objective: gene defect frequency varies in different geographic areas as well as ethnic groups. in this study, the role of factor v leiden mutation in the pathogenesis of preeclampsia syndrome among the pregnant population of northern shore of persian gulf in iran, were considered. materials and methods: betwe...
متن کاملRecurrent Pregnancy Loss in a Subject with Heterozygote Factor V Leiden Mutation; a Case Report
Recurrent pregnancy loss is usually defined as the loss of two or more consecutive pregnancies before 20 weeks of gestation, which occurs in approximately 5% of reproductive-aged women. It has been suggested that women with thrombophilia have an increased risk of pregnancy loss and other adverse pregnancy outcomes. Thrombophilia is an important predisposition to blood clot formation and is cons...
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ژورنال
عنوان ژورنال: Journal of Translational Internal Medicine
سال: 2020
ISSN: 2224-4018
DOI: 10.2478/jtim-2020-0040